Cef-3 Powder for Suspension (Cefixime Trihydrate) || Square Pharmaceuticals Ltd.

Cef-3 Powder for Suspension (Cefixime Trihydrate) || Square Pharmaceuticals Ltd.
[Cef-3 Powder for Suspension
Cefixime Trihydrate
100 mg/5 ml
Square Pharmaceuticals Ltd.
50 ml bottle
Indications
Cefixime is indicated in the following infectious diseases-

Respiratory Tract Infections: Pneumonia, Sinusitis, Pharyngitis and Tonsillitis, Acute Bronchitis and Acute Exacerbations of Chronic Bronchitis (AECB)
Otitis Media
Typhoid
Urinary Tract Infections
Uncomplicated gonorrhea (cervical/urethral).

Therapeutic Class
Third generation Cephalosporins
Pharmacology
Cefixime binds to 1 or more of the penicillin-binding proteins (PBPs) which inhibit the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall, thus inhibiting biosynthesis and arresting cell wall assembly resulting in bacterial cell death.
Dosage & Administration
The usual course of treatment is 7 days. This may be continued for up to 14 days if required. The daily dose can be given in 1–2 divided doses.

Usual dose:

Adult and child over 10 years: 200–400 mg daily
Child over 6 months: 8 mg/kg daily
6 months to 1 year: 75 mg (3.75 ml) daily,
1 to 4 years: 100 mg (5 ml) daily
5 to 10 years: 200 mg (10 ml) daily]
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